WONG

2018:

• Johnson, A. O., Gonzalez Villanueva, M., Tee, K. L. & Wong, T. S. (2018). An engineered constitutive promoter set with broad activity range for Cupriavidus necator H16. ACS Synthetic Biology. doi: 10.1021/acssynbio.8b00136.

2017:

• Johnson, A. O., Gonzalez-Villanueva, M., Wong, L., Steinbuechel, A., Tee, K. L., Peng, X. & Wong, T. S. (2017). Design and application of genetically-encoded malonyl-coA biosensors for metabolic engineering of microbial cell factories. Metabolic Engineering. doi:10.1016/j.ymben.2017.10.011.

• Tee, K. L., Grinham, J., Othusitse, A. M., Gonzalez-Villanueva, M., Johnson, A. O. & Wong, T. S. (2017). An efficient transformation method for the bioplastic-producing "Knallgas" bacterium Ralstonia eutropha H16. Biotechnology Journal. doi: 10.1002/biot.201700081.

• Tee, K. L. & Wong, T. S. (2017). Back to basics: Creating genetic diversity. In Alcalde, M. (Ed), Directed Enzyme Evolution: Advances and Applications (pp. 201-227). Germany: Springer International Publishing.

2016:

• Jajesniak, P., & Wong, T. S. (2016). Rapid construction of recombinant plasmids by QuickStep-Cloning. Methods in Molecular Biology, 1472, 205-214.

2015:

• Jajesniak, P., & Wong, T. S. (2015). From genetic circuits to industrial-scale biomanufacturing: bacterial promoters as a cornerstone of biotechnology. AIMS Bioengineering, 2(3), 277-296.

• Jajesniak, P., & Wong, T. S. (2015). QuickStep-Cloning: a sequence-independent, ligation-free method for rapid construction of recombinant plasmids. Journal of Biological Engineering, 9, 15.

• Warburton, M., Omar Ali, H., Liong, W. C., Othusitse, A. M., Abdullah Zubir, A. Z., Maddock, S., & Wong, T. S. (2015). OneClick: A program for designing focused mutagenesis experiments. AIMS Bioengineering, 2(3), 126-143.

• Johnson, A. O., Gonzalez Villanueva, M., & Wong, T. S. (2015). Engineering Ralstonia eutropha for chemical production. In Industrial Processes and Nanotechnology (Vol. 10). USA: Studium Press LLC.

• Omar Ali, H., Alessa, A. H. A., Al-nuaemi, I. J., & Wong, T. S. (2015). Protein engineering for lignocellulose degradation. In Biodegradation and Bioremediation (Vol. 8). USA: Studium Press LLC.

• Jajesniak, P., & Wong, T. S. (2015). Tapping into biodiversity: From metagenomics to industrial enzymes. In Biodiversity and Conservation (Vol. 2). USA: Studium Press LLC.

2014:

• Tee, K. L., & Wong, T. S. (2014). Directed evolution: A powerful algorithm for advancing synthetic biology. In Singh, V. (Ed.), Applied Synthetic Biology (Vol. 4, pp. 465-497). USA: Studium Press LLC.

• Jajesniak, P., Omar Ali, H., & Wong, T. S. (2014). Carbon dioxide capture and utilization using biological systems: opportunities and challenges. Journal of Bioprocessing & Biotechniques, 4(3), 155.

• Verma, R., Wong, T. S., Schwaneberg, U., & Roccatano, D. (2014). The mutagenesis assistant program. Methods in Molecular Biology, 1179, 279-290.

2013:

• Tee, K. L., & Wong, T. S. (2013). Polishing the craft of genetic diversity creation in directed evolution. Biotechnology Advances, 31(8), 1707-1721.

2012:

• Kuper, J., Tee, K. L., Wilmanns, M., Roccatano, D., Schwaneberg, U., & Wong, T. S. (2012). The role of active-site Phe87 in modulating the organic co-solvent tolerance of cytochrome P450 BM3 monooxygenase. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 68(9), 1013-1017.

2011:

• Lim, E. G., Wang, Z., Tillo, T., Man, K. L., Wong, T. S., & Lai, K. W. (2011). A novel radio propagation and radiation model of the wireless capsule endoscopy in human gastro-intestine (GI) tract. 2011 International SoC Design Conference, ISOCC 2011, 310-312.

2009:

• Wong, T. S., Rajagopalan, S., Freund, S. M., Rutherford, T. J., Andreeva, A., Townsley, F. M., Petrovich, M. & Fersht, A. R. (2009). Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53. Nucleic Acids Research, 37(20), 6765-6783.

• Di Re, M., Sembongi, H., He, J., Reyes, A., Yasukawa, T., Martinsson, P., Bailey, L. J., Goffart, S., Boyd-Kirkup, J. D., Wong, T. S., Fersht, A. R., Spelbrink, J. N., & Holt, I. J. (2009). The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells. Nucleic Acids Research, 37(17), 5701-5713.

• Wong, T. S., Rajagopalan, S., Townsley, F. M., Freund, S. M., Petrovich, M., Loakes, D., & Fersht, A. R. (2009). Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53. Nucleic Acids Research, 37(2), 568-581.

2008:

• Wong, T. S., Roccatano, D., Loakes, D., Tee, K. L., Schenk, A., Hauer, B., & Schwaneberg, U. (2008). Transversion-enriched sequence saturation mutagenesis (SeSaM-Tv+): A random mutagenesis method with consecutive nucleotide exchanges that complements the bias of error-prone PCR. Biotechnology Journal, 3(1), 74-82.

2007:

• Wong, T. S., Roccatano, D., & Schwaneberg, U. (2007). Challenges of the genetic code for exploring sequence space in directed protein evolution. Biocatalysis and Biotransformation, 25(2-4), 229-241.

• Wong, T. S., Roccatano, D., & Schwaneberg, U. (2007). Steering directed protein evolution: Strategies to manage combinatorial complexity of mutant libraries. Environmental Microbiology, 9(11), 2645-2659.

• Kuper, J., Wong, T. S., Roccatano, D., Wilmanns, M., & Schwaneberg, U. (2007). Understanding a mechanism of organic cosolvent inactivation in heme monooxygenase P450BM-3. Journal of the American Chemical Society, 129(18), 5786-5787.

• Wong, T. S., Roccatano, D., & Schwaneberg, U. (2007). Are transversion mutations better? A mutagenesis assistant program analysis on P450 BM-3 heme domain. Biotechnology Journal, 2(1), 133-142.

2006:

• Wong, T. S., Zhurina, D., & Schwaneberg, U. (2006). The diversity challenge in directed protein evolution. Combinatorial Chemistry & High Throughput Screening, 9(4), 271-288.

• Roccatano, D., Wong, T. S., Schwaneberg, U., & Zacharias, M. (2006). Toward understanding the inactivation mechanism of monooxygenase P450 BM-3 by organic cosolvents: a molecular dynamics simulation study. Biopolymers, 83(5), 467-476.

• Wong, T. S., Schwaneberg, U., Sturmer, R., Hauer, B., & Breuer, M. (2006). A filter paper-based assay for laboratory evolution of hydrolases and dehydrogenases. Combinatorial Chemistry & High Throughput Screening, 9(4), 289-293.

• Wong, T. S., Roccatano, D., Zacharias, M., & Schwaneberg, U. (2006). A statistical analysis of random mutagenesis methods used for directed protein evolution. Journal of Molecular Biology, 355(4), 858-871.

• Schenk, A., Wong, T. S., Roccatano, D., Hauer, B., & Schwaneberg, U. (2006). Sequence saturation mutagenesis (SeSaM) of a gene. BioSpektrum, 12(3), 277-279.

2005:

• Wong, T. S., Wu, N., Roccatano, D., Zacharias, M., & Schwaneberg, U. (2005). Sensitive assay for laboratory evolution of hydroxylases toward aromatic and heterocyclic compounds. Journal of Biomolecular Screening, 10(3), 246-252.

• Wong, T. S., Tee, K. L., Hauer, B., & Schwaneberg, U. (2005). Sequence saturation mutagenesis with tunable mutation frequencies. Analytical Biochemistry, 341(1), 187-189.

• Roccatano, D., Wong, T. S., Schwaneberg, U., & Zacharias, M. (2005). Structural and dynamic properties of cytochrome P450 BM-3 in pure water and in a dimethylsulfoxide/water mixture. Biopolymers, 78(5), 259-267.

2004:

• Wong, T. S., Arnold, F. H., & Schwaneberg, U. (2004). Laboratory Evolution of Cytochrome P450 BM-3 Monooxygenase for Organic Cosolvents. Biotechnology & Bioengineering, 85(3), 351-358.

• Wong, T. S., Tee, K. L., Hauer, B., & Schwaneberg, U. (2004). Sequence saturation mutagenesis (SeSaM): a novel method for directed evolution. Nucleic Acids Research, 32(3), e26.

2003:

• Wong, T. S., & Schwaneberg, U. (2003). Protein engineering in bioelectrocatalysis. Current Opinion in Biotechnology, 14(6), 590-596.